Cryptic crossword clue
Mix fluid after rinse 10

The most common and most likely answer to this crossword clue is the 10 letter word FRATERNISE

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "Mix" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case mix = fraternise.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does FRATERNISE mean?

FRATERNISE verb
  1. To associate with others in a brotherly or friendly manner.
  2. To associate as friends with an enemy, in violation of duty.
  3. To have an intimate or sexual relationship with a forbidden member of the opposite sex; as, in some cases, football players with cheerleaders.

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