The most common and most likely answer to this crossword clue is the 7 letter word SWIZZLE
I've seen this crossword clue in The Daily Telegraph
S
W
I
Z
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More clues leading to the result SWIZZLE
Buddy explains!
The straight part
We know that "Mixed alcoholic drink/great disappointment" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case mixed alcoholic drink/great disappointment = swizzle.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does SWIZZLE mean?
SWIZZLE noun- A beverage of water and vinegar, often seasoned with ginger and sweetened with molasses, honey, or similar.
- Any of various kinds of alcoholic drink.
- To stir or mix.
- To permute bits.
- To convert portable symbols or positions to memory-dependent pointers during deserialization.
- To drink; to swill.