The most common and most likely answer to this crossword clue is the 5 letter word DEWAX
D
E
W
A
X
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The straight part
We know that "remove a sticky substance" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case remove a sticky substance = dewax.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DEWAX mean?
DEWAX verb- To remove wax from a material or from a surface.