The most common and most likely answer to this crossword clue is the 5 letter word ULCER
I've seen this crossword clue in Financial Times
U
L
C
E
R
More clues leading to the result ULCER
- Faceless governor bypasses constant health problem
- Unsound element in awful ceramics
- Sore, but pulls clear reducing the odds
- Complaint from northbound hermit lacking solitude on vacation
- Awfully cruel medical condition
- Recluse, leaving the Home Counties, turned up with an abscess
- Sore about breaking silly rule
- Persistent source of evil, he escapes Poirot deviously?
- Monarch heading off having acquired cold sore
- Disintegrating tissue recalled dire club sandwiches
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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does ULCER mean?
ULCER noun- An open sore of the skin, eyes or mucous membrane, often caused by an initial abrasion and generally maintained by an inflammation and/or an infection.
- Peptic ulcer
- Anything that festers and corrupts like an open sore; a vice in character.