The most common and most likely answer to this crossword clue is the 2 plus 6 letter word LA MANCHA
I've seen this crossword clue in The Guardian
L
A
M
A
N
C
H
A
More clues leading to the result LA MANCHA
- Monk controls a new church in Don’s area
- Spanish region’s alternately lean, mean, nice head
- The Italian guys, second of which docked somewhere in Spain
- The French fellow and companion going to a Spanish location
- Priest leads children through North American wine region
- City gent’s tea – whence Quixote did come?
Buddy explains!
The straight part
We know that "Don’s area" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case don’s area = la mancha.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.