Cryptic crossword clue
Monkey in pair vacated room for parasitic creature 8

The most common and most likely answer to this crossword clue is the 8 letter word TAPEWORM

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Buddy explains!

The straight part
We know that "parasitic creature" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case parasitic creature = tapeworm.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does TAPEWORM mean?

TAPEWORM noun
  1. Any parasitical worm of the class or infraclass Cestoda, which infest the intestines of animals, including humans, often infecting different host species during their life cycle.
  2. Infection by tapeworms.

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