Cryptic crossword clue
Moon study transforming lonely egos 10

The most common and most likely answer to this crossword clue is the 10 letter word SELENOLOGY

S
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Buddy explains!

The straight part
We know that "Moon study" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case moon study = selenology.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SELENOLOGY mean?

SELENOLOGY noun
  1. The scientific study of the Moon.

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