Cryptic crossword clue
More sick? Pill, erythromycin will contain 5

The most common and most likely answer to this crossword clue is the 5 letter word ILLER

I
L
L
E
R

Buddy explains!

The straight part
We know that "More sick" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case more sick = iller.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ILLER mean?

ILLER adjective
  1. Evil; wicked (of people).
  2. Morally reprehensible (of behaviour etc.); blameworthy.
  3. Indicative of unkind or malevolent intentions; harsh, cruel.
  4. Unpropitious, unkind, faulty, not up to reasonable standard.
  5. Unwell in terms of health or physical condition; sick.
  6. Having an urge to vomit.
  7. (hip-hop slang) Sublime, with the connotation of being so in a singularly creative way.
  8. Extremely bad (bad enough to make one ill). Generally used indirectly with to be.
  9. Unwise; not a good idea.

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