The most common and most likely answer to this crossword clue is the 10 letter word LEXICOLOGY
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More clues leading to the result LEXICOLOGY
Buddy explains!

The straight part
We know that "semantics" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case semantics = lexicology.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does LEXICOLOGY mean?
LEXICOLOGY noun- The part of linguistics that studies words, their nature and meaning, words' elements, relations between words including semantic relations, words groups and the whole lexicon.
- A specific theory concerning the lexicon.