The most common and most likely answer to this crossword clue is the 4 plus 4 letter word SKIN TEST
I've seen this crossword clue in The Times
S
K
I
N
T
E
S
T
More clues leading to the result SKIN TEST
- Most cleaned out for this medical procedure?
- Extremely poor way to determine allergy?
- Medical assessment most impoverished?
- Extremely poor check for 3, perhaps
- Experiment on the surface most in need of funds?
- Medical examination that’s most poor, might one suppose?
- Superficial check on the most impoverished?
- Poorest procedure to determine allergy
Buddy explains!

The straight part
We know that "medical procedure" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case medical procedure = skin test.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.