The most common and most likely answer to this crossword clue is the 8 letter word HORNIEST
H
O
R
N
I
E
S
T
Buddy explains!
The straight part
We know that "being most ready to do it" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case being most ready to do it = horniest.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does HORNIEST mean?
HORNIEST adjective- Hard or bony, like an animal's horn.
- Having horns.
- Sexually aroused.
- Sexually arousing.