Cryptic crossword clue
Most high and mighty at this huge gathering 10

The most common and most likely answer to this crossword clue is the 10 letter word HAUGHTIEST

I've seen this crossword clue in Independent
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Buddy explains!

The straight part
We know that "Most high and mighty" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case most high and mighty = haughtiest.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does HAUGHTIEST mean?

HAUGHTIEST adjective
  1. Conveying in demeanour the assumption of superiority; disdainful, supercilious.

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