Cryptic crossword clue
Most horrible thoroughfare falls within copper’s territory 10

The most common and most likely answer to this crossword clue is the 10 letter word BEASTLIEST

I've seen this crossword clue in The Guardian
B
E
A
S
T
L
I
E
S
T

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does BEASTLIEST mean?

BEASTLIEST adjective
  1. Pertaining to, or having the form, nature or habits of, a beast.
  2. Similar to the nature of a beast; contrary to the nature and dignity of man
  3. Abominable.
  4. (of computing hardware) Powerful, having a powerful appearance

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