Cryptic crossword clue
Most repulsive, horrible, evil saint 6

The most common and most likely answer to this crossword clue is the 6 letter word VILEST

V
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Buddy explains!

The straight part
We know that "Most repulsive" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case most repulsive = vilest.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does VILEST mean?

VILEST adjective
  1. Morally low; base; despicable.
  2. Causing physical or mental repulsion; horrid.

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