The most common and most likely answer to this crossword clue is the 8 letter word NASTIEST
I've seen this crossword clue in The Times
N
A
S
T
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T
More clues leading to the result NASTIEST
- Most revolting wine kept in secluded place
- Residence stocks wine that’s extremely unpleasant
- Most awful new wine is French
- The most disgusting Italian wine in den
- Somewhere comfortable drinking wine? That’s most unpleasant!
- Out of sorts titaness can be most unpleasant
- Article about Stones touring that is most unpleasant
- Most unpleasant wine found in cosy home
- Most horrible stain is dispersed by English saint
- House wine bottled — it's extremely bad
Buddy explains!

The straight part
We know that "Most revolting" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case most revolting = nastiest.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does NASTIEST mean?
NASTIEST adjective- Dirty, filthy.
- Contemptible, unpleasant (of a person).
- Objectionable, unpleasant (of a thing); repellent, offensive.
- Indecent or offensive; obscene, lewd.
- Spiteful, unkind.
- Awkward, difficult to navigate; dangerous.
- Grave or dangerous (of an accident, illness etc.).
- Formidable, terrific; wicked.