The most common and most likely answer to this crossword clue is the 7 letter word CLOSEST
I've seen this crossword clue in The Times
C
L
O
S
E
S
T
More clues leading to the result CLOSEST
- Miss is in court being incomparably careful
- Most stuffy little room in which son hides
- Most tight finishes will get tense
- Most devoted son found in privy
- Most intimate undies finally put in wardrobe
- . Most dear son trapped in cupboard
- Most proximate dead-end road on street
- Gets defeated in court and most strictly confined
Buddy explains!

The straight part
We know that "Most stuffy" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case most stuffy = closest.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does CLOSEST mean?
CLOSEST verb- (physical) To remove a gap.
- (social) To finish, to terminate.
- To come or gather around; to enclose; to encompass; to confine.
- To have a vector sum of 0; that is, to form a closed polygon.
- Closed, shut.
- Narrow; confined.
- At a little distance; near.
- Intimate; well-loved.
- Oppressive; without motion or ventilation; causing a feeling of lassitude.
- (Ireland, England, Scotland) Hot, humid, with no wind.
- (of a vowel) Articulated with the tongue body relatively close to the hard palate.
- Strictly confined; carefully guarded.
- Out of the way of observation; secluded; secret; hidden.
- Nearly equal; almost evenly balanced.
- Short.
- Dense; solid; compact.
- Concise; to the point.
- Difficult to obtain.
- Parsimonious; stingy.
- Adhering strictly to a standard or original; exact.
- Accurate; careful; precise; also, attentive; undeviating; strict.
- Marked, evident.