Cryptic crossword clue
Mothers etc with yen twice suffering what no husbands can undergo 12

The most common and most likely answer to this crossword clue is the 12 letter word HYSTERECTOMY

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Buddy explains!

The straight part
We know that "what no husbands can undergo" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case what no husbands can undergo = hysterectomy.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does HYSTERECTOMY mean?

HYSTERECTOMY noun
  1. The surgical procedure to remove all of or part of the uterus.

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