Cryptic crossword clue
Motion sickness controls Y-chromosome in adult during muscular contraction  8

The most common and most likely answer to this crossword clue is the 8 letter word MYOTONIA

M
Y
O
T
O
N
I
A

Buddy explains!

The straight part
We know that "muscular contraction" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case muscular contraction = myotonia.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MYOTONIA mean?

MYOTONIA noun
  1. A symptom of several muscular disorders characterized by the slow relaxation of the muscles after voluntary contraction or electrical stimulation.

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