The most common and most likely answer to this crossword clue is the 10 letter word AUTOSTRADA
I've seen this crossword clue in The Times
A
U
T
O
S
T
R
A
D
A
More clues leading to the result AUTOSTRADA
- Motorway route cut short as data misread
- Driving fast? It's the Italian way!
- Travelling most of Saturday to a Continental motorway
- Run to fill golden pancake ?- in Italy, it’s the quickest way
- Gold violin cases nearly closed a road in Italy
- Car moves quickly over a Roman road?
- A sad tutor going wild on a road abroad
Buddy explains!

The straight part
We know that "Motorway" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case motorway = autostrada.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does AUTOSTRADA mean?
AUTOSTRADA noun- A motorway in Italy (and some other countries)