Cryptic crossword clue
Mum, on air, drunk on unknown wine 6

The most common and most likely answer to this crossword clue is the 6 letter word SHIRAZ

S
H
I
R
A
Z


Buddy explains!

The straight part
We know that "wine" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case wine = shiraz.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SHIRAZ mean?

SHIRAZ noun
  1. A variety of black grape used to make wine
  2. A wine made from these grapes

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