The most common and most likely answer to this crossword clue is the 6 letter word FLEXOR
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More clues leading to the result FLEXOR
Buddy explains!
The straight part
We know that "Muscle" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case muscle = flexor.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does FLEXOR mean?
FLEXOR noun- A muscle whose contraction acts to bend a joint or limb.