The most common and most likely answer to this crossword clue is the 3 letter word UKE
I've seen this crossword clue in The Times
U
K
E
More clues leading to the result UKE
- Cat not wanting piano as musical instrument
- Music producer Posh & Becks regularly put up
- Instrument from east associated with this country
- Music maker, oddly overlooked, but keen
- Instrument of torture finally taken on by monarchy
- Instrument, funkier on regular basis
- Instrument of torture ultimately found by kingdom
- Ellington? Not his first instrument!
- Tiny Tim played this punk gem regularly
- Religious writer and physician taking top off instrument
Buddy explains!

The straight part
We know that "Music maker" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case music maker = uke.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does UKE mean?
UKE noun- A small four-stringed guitar.
- The training partner against whom tori performs a move.
- (Japanese fiction) A passive or submissive male fictional character in a same-sex relationship; a bottom.