The most common and most likely answer to this crossword clue is the 10 letter word TRUMPETERS
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More clues leading to the result TRUMPETERS
Buddy explains!

The straight part
We know that "Musicians/ strum, first to last enthralling boy (10)" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case musicians/ strum, first to last enthralling boy (10) = trumpeters.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does TRUMPETERS mean?
TRUMPETERS noun- Someone who plays a trumpet.
- Any of three species of bird in the family Psophiidae from South America named for the trumpeting threat call of the males.
- Any of a number of breeds of fancy pigeon (variety of domestic pigeon (Columba livia), originally bred for their peculiar gurgling voice, a prolonged coo called "trumpeting" or "drumming").
- One who proclaims, publishes, or denounces.
- An American swan (Cygnus buccinator) with a very loud honk.
- A perciform fish of the family Latridae, native to Australia, New Zealand and Chile.