The most common and most likely answer to this crossword clue is the 4 letter word ACNE
I've seen this crossword clue in The Daily Telegraph
A
C
N
E
More clues leading to the result ACNE
- Spots all cheetahs need evidently, first of all
- Spots what sounds like an East End carriage?
- Spots: a card contains any number
- Spots in part of East London, as locals may pronounce it?
- A schoolkid's problem covered by Isaac Newton
- Spots of corrosion finally found in service
- Complaint rejected in umpteen cases
- Complaint coming from Isaac Newton
- Spots first of nuns entering a church
- Unsightly condition Isaac Newton bears
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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does ACNE mean?
ACNE noun- A skin condition, usually of the face, that is common in adolescents. It is characterised by red pimples, and is caused by the inflammation of sebaceous glands through bacterial infection.
- A pattern of blemishes in an area of skin resulting from the skin condition.