Cryptic crossword clue
Nasal problem: factor in blood disorder is in it 8

The most common and most likely answer to this crossword clue is the 8 letter word RHINITIS

I've seen this crossword clue in Independent
R
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Buddy explains!

The straight part
We know that "Nasal problem" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case nasal problem = rhinitis.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does RHINITIS mean?

RHINITIS noun
  1. Inflammation of the mucous membranes of the nose.

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