Cryptic crossword clue
Nasty lesion found beneath foot 6

The most common and most likely answer to this crossword clue is the 6 letter word INSOLE

I've seen this crossword clue in The Guardian
I
N
S
O
L
E


Buddy explains!

The straight part
We know that "found beneath foot" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case found beneath foot = insole.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does INSOLE mean?

INSOLE noun
  1. The inside sole of a shoe or other footwear.

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