Cryptic crossword clue
Natural defence for small boy absorbing brief life in retrospect

The most common and most likely answer to this crossword clue is the 8 letter word ANTIBODY

I've seen this crossword clue in The Guardian
A
N
T
I
B
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Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ANTIBODY mean?

ANTIBODY noun
  1. A protein produced by B-lymphocytes that binds to a specific antigen.

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