The most common and most likely answer to this crossword clue is the 5 letter word VIXEN
I've seen this crossword clue in The Guardian
V
I
X
E
N
More clues leading to the result VIXEN
- Spiteful woman from NE14 returned
- Fox TV’s latest: 9/11 vacuously presented
- Volume 9: Mid-Kent
- Nearly new 14 turned up, one chased by 15
- 7 across’s running mate has characteristic of 17 down
- Rudolph’s partner, foxy lady?
- Bilious woman needing some Kleenex I’ve passed over
- Earth mother?
- Sex symbol abandons us to claim single kiss with foxy lady
- Kiss precedes drug dissolved in wine for ill-tempered female
Buddy explains!

The straight part
We know that "one chased by 15" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case one chased by 15 = vixen.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does VIXEN mean?
VIXEN noun- A female fox.
- A malicious, quarrelsome or temperamental woman.
- A racy or salacious woman.
- A wife who has sex with other men with her husband's consent.