Cryptic crossword clue
Neatly trim fractured cranium with end of knife 8

The most common and most likely answer to this crossword clue is the 8 letter word MANICURE

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "Neatly trim" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case neatly trim = manicure.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MANICURE mean?

MANICURE noun
  1. A cosmetic treatment for the fingernails.
  2. A manicurist.
MANICURE verb
  1. To trim the fingernails

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