Cryptic crossword clue
Nervous distention – a painful condition 10

The most common and most likely answer to this crossword clue is the 10 letter word TENDONITIS

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The cryptic/wordplay part
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This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
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What does TENDONITIS mean?

TENDONITIS noun
  1. Inflammation of a tendon.

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