The most common and most likely answer to this crossword clue is the 7 letter word INFERNO
I
N
F
E
R
N
O
More clues leading to the result INFERNO
- Conclude negative vote's a disaster
- Conclude nothing can get to grips with northern hell
- Deduce nitric oxide produces large fire
- Conclude working in retirement is hell
- Place of horror? Conclude the answer is negative
- Big fire I observed primarily consuming northern plant
- One may rage, having to assume refusal
- Fire or non-fire, possibly
- Fire out of control? Suppose not
- Fire raging with no end of destruction?
Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does INFERNO mean?
INFERNO noun- A place or situation resembling Hell.
- A large fire, a conflagration.