Cryptic crossword clue
Neutered drink at work sent back without a smile

The most common and most likely answer to this crossword clue is the 8 letter word PO-FACED

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "without a smile" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case without a smile = po-faced.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does PO-FACED mean?

PO-FACED adjective
  1. Wearing a particularly stern and disapproving expression; humourless; priggish.
  2. Poker-faced.

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