The most common and most likely answer to this crossword clue is the 4 letter word RENO
R
E
N
O
More clues leading to the result RENO
- Republican one backed in Nevada city
- Rex and Brian in a gambling centre
- City of divorces with children obviously missing out a lot
- Northern half of famous gambling centre
- US city rejecting any of educational basics
- Seen on US map, it takes one right back
- To which you go married, coming back single. Right?
- Not a place to get divorced
- On and on about American city
- Gambling place in future Noida
Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does RENO mean?
RENO noun- An act, or the process, of renovating.
- Regeneration.