Cryptic crossword clue
New regret about Spike Milligan’s introduction 11

The most common and most likely answer to this crossword clue is the 11 letter word REPLACEMENT

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Buddy explains!

The straight part
We know that "New" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case new = replacement.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does REPLACEMENT mean?

REPLACEMENT noun
  1. A person or thing that takes the place of another; a substitute.
  2. The act of replacing something.
  3. The removal of an edge of crystal, by one plane or more.

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