Cryptic crossword clue
Newspaper's operative set of principles 7

The most common and most likely answer to this crossword clue is the 7 letter word ORGANON

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The straight part
We know that "set of principles" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case set of principles = organon.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ORGANON mean?

ORGANON noun
  1. A set of principles that are used in science or philosophy.
  2. The name given by Aristotle's followers to his six works on logic.

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