The most common and most likely answer to this crossword clue is the 8 letter word FLORENCE
F
L
O
R
E
N
C
E
More clues leading to the result FLORENCE
- Prof finally learning about boring north-eastern city
- Maybe use foil to wrap large golden girl
- Enforce changes around Latvian capital, European city
- Criminal taking in brother in Tuscan city
- Nightingale in the city?
- Nightingale found in Italy
- Look right through barrier at site of Brunelleschi’s 7
- City criminal penetrates centre for solid gold? On the contrary
- Italian city girl
- City left men inside barrier
Buddy explains!

The straight part
We know that "Nightingale/city" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case nightingale/city = florence.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.