The most common and most likely answer to this crossword clue is the 5 plus 8 letter word PANIC STRICKEN
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More clues leading to the result PANIC STRICKEN
Buddy explains!
The straight part
We know that "very anxious" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case very anxious = panic stricken.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does PANIC STRICKEN mean?
PANIC STRICKEN adjective- Very frightened, and unable to react sensibly because of panic.