Cryptic crossword clue
No 1 sign diet at fault? 11

The most common and most likely answer to this crossword clue is the 11 letter word INDIGESTION

I
N
D
I
G
E
S
T
I
O
N

Buddy explains!

The straight part
We know that "No 1 sign diet at fault" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case no 1 sign diet at fault = indigestion.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does INDIGESTION mean?

INDIGESTION noun
  1. A condition of heartburn, nausea, etc. most often caused by eating too quickly.

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