The most common and most likely answer to this crossword clue is the 11 letter word MONARCHISTS
I've seen this crossword clue in The Daily Telegraph
M
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More clues leading to the result MONARCHISTS
Buddy explains!

The straight part
We know that "Cromwell’s lot? Certainly not" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case cromwell’s lot? certainly not = monarchists.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does MONARCHISTS mean?
MONARCHISTS noun- An advocate of, or believer in, monarchy.