Cryptic crossword clue
No rest, sadly, for drug addict 6

The most common and most likely answer to this crossword clue is the 6 letter word STONER

I've seen this crossword clue in Independent
S
T
O
N
E
R

Buddy explains!

The straight part
We know that "drug addict" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case drug addict = stoner.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does STONER mean?

STONER noun
  1. One who stones.
  2. A machine to remove the stones (pits) from fruit.
  3. A habitual user of cannabis.

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