Cryptic crossword clue
Non-drinker in row causes giggle 6

The most common and most likely answer to this crossword clue is the 6 letter word TITTER

I've seen this crossword clue in The Times
T
I
T
T
E
R


Buddy explains!

The straight part
We know that "giggle" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case giggle = titter.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does TITTER mean?

TITTER noun
  1. A nervous or somewhat repressed giggle.
TITTER verb
  1. To laugh or giggle in a somewhat subdued or restrained way, as from nervousness or poorly-suppressed amusement.
  2. To teeter; to seesaw.
TITTER noun
  1. (chiefly in the plural) A woman's breast.

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