The most common and most likely answer to this crossword clue is the 10 letter word ANTAGONIST
I've seen this crossword clue in The Daily Telegraph
A
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T
A
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More clues leading to the result ANTAGONIST
- Stagnation shocked opponent
- One against one not against changes
- Stagnation irritated rival
- Opponent created stagnation
- Not against making an enemy
- Worker with muscle — bolshy type?
- Adversary who’s not against revolutionary
- Not against roughing up an opponent
- One’s against, not for resolution
- Shakespeare character almost accepting silver, good man’s enemy
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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does ANTAGONIST mean?
ANTAGONIST noun- An opponent or enemy.
- One who antagonizes or stirs.
- A chemical that binds to a receptor but does not produce a physiological response, blocking the action of agonist chemicals.
- (authorship) The main character or force opposing the protagonist in a literary work or drama.
- A muscle that acts in opposition to another.