Cryptic crossword clue
Not as giants, flexing muscles 11

The most common and most likely answer to this crossword clue is the 11 letter word ANTAGONISTS

I've seen this crossword clue in The Daily Telegraph
A
N
T
A
G
O
N
I
S
T
S

Buddy explains!

The straight part
We know that "muscles" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case muscles = antagonists.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ANTAGONISTS mean?

ANTAGONISTS noun
  1. An opponent or enemy.
  2. One who antagonizes or stirs.
  3. A chemical that binds to a receptor but does not produce a physiological response, blocking the action of agonist chemicals.
  4. (authorship) The main character or force opposing the protagonist in a literary work or drama.
  5. A muscle that acts in opposition to another.

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