Cryptic crossword clue
Not on — Telegraph, evidently worried, showed sign of panic 15

The most common and most likely answer to this crossword clue is the 15 letter word HYPERVENTILATED

I've seen this crossword clue in The Guardian
H
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P
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Buddy explains!

The straight part
We know that "showed sign of panic" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case showed sign of panic = hyperventilated.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does HYPERVENTILATED mean?

HYPERVENTILATED verb
  1. To breathe quickly and deeply, especially at an abnormally rapid rate.

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