The most common and most likely answer to this crossword clue is the 6 letter word POORLY
I've seen this crossword clue in The Sunday Telegraph
P
O
O
R
L
Y
Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does POORLY mean?
POORLY adverb- In a poor manner or condition; without plenty, or sufficiency, or suitable provision for comfort.
- With little or no success; indifferently; with little profit or advantage.
- Meanly; without spirit.
- Without skill or merit.
- In a negative manner; with disapproval.
- Ill, unwell, sick