Cryptic crossword clue
Note colleague as little as possible 9

The most common and most likely answer to this crossword clue is the 9 letter word MINIMALLY

I've seen this crossword clue in The Times
M
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Buddy explains!

The straight part
We know that "as little as possible" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case as little as possible = minimally.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MINIMALLY mean?

MINIMALLY adverb
  1. In a minimal way; to the least extent.

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