Cryptic crossword clue
Note enclosed in letter found by large stream 6

The most common and most likely answer to this crossword clue is the 6 letter word RUNNEL

I've seen this crossword clue in The Guardian
R
U
N
N
E
L

Buddy explains!

The straight part
We know that "stream" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case stream = runnel.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does RUNNEL mean?

RUNNEL noun
  1. A small stream, a rivulet.
RUNNEL verb
  1. To create channels for directing the flow of liquid.

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