Cryptic crossword clue
Note, going round Siena, grub regularly seen? 8

The most common and most likely answer to this crossword clue is the 8 letter word LINGUINE

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Buddy explains!

The straight part
We know that "Note, going round Siena, grub regularly seen?" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case note, going round siena, grub regularly seen? = linguine.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does LINGUINE mean?

LINGUINE noun
  1. Ribbons of pasta, cut from a sheet, not as wide as tagliatelle.

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