Cryptic crossword clue
Note my oddly original word 6

The most common and most likely answer to this crossword clue is the 6 letter word ETYMON

I've seen this crossword clue in The Guardian
E
T
Y
M
O
N


Buddy explains!

The straight part
We know that "original word" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case original word = etymon.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ETYMON mean?

ETYMON noun
  1. The source word, or words, of a given word or expression.

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