Cryptic crossword clue
Note very loud Scene VI set out to provide potency 13

The most common and most likely answer to this crossword clue is the 13 letter word EFFECTIVENESS

I've seen this crossword clue in The Daily Telegraph
E
F
F
E
C
T
I
V
E
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E
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S

Buddy explains!

The straight part
We know that "potency" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case potency = effectiveness.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does EFFECTIVENESS mean?

EFFECTIVENESS noun
  1. The property of being effective, of achieving results.
  2. The capacity or potential for achieving results.
  3. The degree to which something achieves results.

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